Gene therapy holds a promising future for bridging the gap between the disciplines of\nmedicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been\nadvancing by leaps and bounds. They are transforming the conventional approaches into more\nprecise and preventive ones that may limit the need of using drugs and surgery. The oral cavity is\none of the most accessible areas for the clinical applications of gene therapy for various oral tissues.\nThe idea of genetic engineering has become more exciting due to its advantages over other treatment\nmodalities. For instance, the body is neither subjected to an invasive surgery nor deep wounds,\nnor is it susceptible to systemic effects of drugs. The aim of this article is to review the gene therapy\napplications in the field of dentistry. In addition, therapeutic benefits in terms of treatment of diseases,\nminimal invasion and maximum outcomes have been discussed.
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